In 1935, Citron had her first major critically acclaimed solo show titled "Feminanities," at the Midtown Gallery in New York City. The work in this show addressed issues of gender and sexism in a satirical light. In the early 1940s, Citron's work shifted towards a more abstract style.
She joined Atelier 17, a renowned printmaking school and studio and began experimenting with new styles and innovative techniques. A 1960 solo exhibit in Zagreb was the first time an American artist had mounted such a show in Yugoslavia.