Pamela Salyer, despite her artistic work, has a background in chemistry and biology. Those fields inspired her later artistic works which explored the fields of mixed media. Among them are works with acrylics, paper, gels, fabrics, ink, charcoal, and several others. Combining those mediums and her scientific background has led to an artistic focus on the products of nature like flowers and insects. Later in life she would attend the Open College of Arts in the UK and then settle in Knoxville, Tennessee, where she has showcased her work to the present day.